Pharmacotherapy of Diabetes: New Developments: Improving Life and Prognosis for Diabetic Patients

By Carl Erik Mogensen
Publisher: Springer
Number Of Pages: 318
Publication Date: 2007-09-05
ISBN-10 / ASIN: 0387697365
ISBN-13 / EAN: 9780387697369
Binding: Hardcover

Book Description:

In the United States, 20.8 million children and adults, 7% of the population, have diabetes. While an estimated 14.6 million have been diagnosed, 6.2 million have yet to be diagnosed. Worldwide diabetes afflicts 150 million people. The World Health Organization estimates that by 2025 that figure will double. Diabetes is responsible for more deaths than AIDS and breast cancer, combined. It is a leading cause of blindness, kidney failure, amputations, heart complications and stroke.

Treatment of Type 1 and Type diabetes has changed radically over the past few years. There are new opportunities for treating the key abnormality in diabetes, increased blood glucose, by effective agents such as new insulin preparations and oral agents.

Increasing so-called non-glycemic intervention is of prime importance. Blood pressure lowering therapies, anti-cholesterol strategies, and specific treatment related to complications is becoming increasingly important.

Pharmacotherapy of Diabetes is a unique, invaluable guide to all aspects of the pharmacological treatment of diabetes, covering basic concepts and an in-depth review of current and future therapies. This work provides an overview for the new changes in therapies that can be implemented in clinical practice and treatment of the diabetic patient.

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Glucokinase And Glycemic Disease: From Basics to Novel Therapeutics

Author: F. M. Matschinsky (Editor), M. A. Magnuson (Editor)
Product Details
406 pages, S. Karger Publishers (USA) (June 3, 2004) $234.75
Format: 2.5MB PDF
ISBN / ASIN: 3805577443
Summary:
The glucose-phosphorylating enzyme glucokinase (also known as hexokinase IV) plays a preeminent role as a glucose sensor and regulatory metabolic enzyme. The implications of this central position of glucokinase for the understanding and treatment of diabetes mellitus are far reaching. This book addresses the molecular and human genetic, as well as the physiological-chemical and pharmacological aspects of the role glucokinase plays in glucose homeostasis and diseases of glucose metabolism, and how the enzyme serves as the drug target for the treatment of diabetes mellitus. The collection of assays by a team of internationally renowned authors includes basic science chapters dealing with the enzymology, structure and the kinetics of hexokinases, essays describing the biochemical genetics of glucokinase-linked hypo- and hyperglycemia syndromes, and papers that discuss the diverse roles of the enzyme in a variety of tissues. 72981431

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Type 2 Diabetes, Pre-Diabetes, and the Metabolic Syndrome

Type 2 Diabetes, Pre-Diabetes, and the Metabolic Syndrome

By Ronald A. Codario
Publisher: Humana Press
Number Of Pages: 272
Publication Date: 2005-05-15
ISBN-10 / ASIN: 1588294714
ISBN-13 / EAN: 9781588294715
Binding: Hardcover
Book Description:

Well-known and highly respected diabetes authority Ronald A. Codario, MD, details for busy primary care practitioners the state of the art in diagnosing and managing diabetes, as well as in reducing patient risk factors. Using an evidence-based approach, Dr. Codario explains, in simple clinical terms that avoid the complexity of much larger textbooks, our latest understanding of the pathophysiology of diabetes, its treatment with insulin and oral agents, and the management of its risk factors. The author also extensively reviews such major topics as the metabolic syndrome, the role of exercise and nutrition, and the key issues associated with the use of herbs and nutraceuticals. Also included are continuing medical education (CME) questions that provide the opportunity to acquire up to a maximum of 10 AMA/PRA category 1 CME credits. For the past 15 years, the author has given CME lectures on diabetes throughout the country.

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Diabetes and Cardiovascular Disease

Diabetes and Cardiovascular Disease

By
Publisher: Humana Press
Number Of Pages: 672
Publication Date: 2005-05-25
Sales Rank: 906047
ISBN / ASIN: 1588294137
EAN: 9781588294135
Binding: Hardcover
Manufacturer: Humana Press
Studio: Humana Press
Average Rating: 0
Total Reviews: 0
Book Description:

This extensively updated and expanded second edition reflects new research, advances in clinical care, and the growing recognition that diabetes mellitus is a risk factor for cardiovascular disease. Written for the practicing clinician as a comprehensive review of diabetic vascular disease, the book both explains the basic pathophysiology of the disease and details the latest diagnostic and therapeutic approaches. The authors have added new chapters on percutaneous interventional therapy in cardiac and peripheral vascular disease, cardiovascular surgery in diabetes, therapeutic interventions to improve endothelial function in diabetes, PARP activation and nitrosative stress in the development of the cardiovascular system, and PPARs and their emerging role in vascular biology, inflammation, and atherosclerosis.

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Closed-Loop Control of Blood Glucose

Closed-Loop Control of Blood Glucose

By Frederick Chee, Tyrone Fernando,


Publisher: Springer
Number Of Pages: 157
Publication Date: 2007-10-01
Sales Rank: 1123474
ISBN / ASIN: 3540740309
EAN: 9783540740308
Binding: Hardcover
Manufacturer: Springer
Studio: Springer
Average Rating: 0
Total Reviews: 0
Book Description:



This book presents the field of closed-loop blood glucose control in a simple manner. This includes the hardware and "software" components that make up the control system. The hardware components involved the different types of glucose sensors available (invasive, minimally-invasive and non-invasive) and the different types of insulin. The software component represents the approaches that translate a given blood glucose reading to an appropriate insulin rate. Some of these approaches applied mathematical sciences to model the underlying system and formulate mathematical solutions. Examples are given on how mathematical models are formulated as well as the control algorithms that stem from mathematical exercises. This book describes from a functional level, the basic physiology of blood glucose regulation during fasting and meal. iT will serve as a useful reference to researches in this area of research to understand the fundamentals involved in blood glucose regulation and to gather most recent advancements in diabetes management.

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Diabetes Management in Primary Care, 2007

Diabetes Management in

Primary Care, 2007

By Jeff Unger
Publisher: Lippincott Williams & Wilkins
Number Of Pages: 712
Publication Date: 2007-03-01
Sales Rank: 138830
ISBN / ASIN: 0781787629
EAN: 9780781787628
Binding: Paperback
Manufacturer: Lippincott Williams & Wilkins
Studio: Lippincott Williams & Wilkins
Average Rating: 5
Total Reviews: 2
Book Description:


This book offers primary care physicians evidence-based guidelines for evaluating and treating all patients with diabetes. It covers all aspects of outpatient and hospital-based diabetes care for all age groups, and includes behavioral interventions for enhancing patient adherence. Coverage includes fine-tuning glycemic management with computerized self-blood glucose monitoring software, evaluating and treating patients with metabolic syndrome and polycystic ovary syndrome, managing mental illness in patients with diabetes, and prevention of microvascular and macrovascular complications. The book discusses newer insulin therapy protocols, insulin delivery devices such as pumps, pens, and inhaled insulin, and novel pharmacotherapies including incretin mimetics and DPP-IV inhibitors

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