Thursday, November 8, 2007

Enzymes: A Practical Introduction to Structure, Mechanism, and Data Analysis


Enzymes: A Practical Introduction to Structure, Mechanism, and Data Analysis

By Robert A. Copeland
Publisher: Wiley-VCH
Number Of Pages: 397
Publication Date: 2000-03-15
Sales Rank: 449250
ISBN / ASIN: 0471359297
EAN: 9780471359296
Binding: Hardcover
Total Reviews: 5

Book Description:

Fully updated and expanded-a solid foundation for understanding experimental enzymology.

This practical, up-to-date survey is designed for a broad spectrum of biological and chemical scientists who are beginning to delve into modern enzymology. Enzymes, Second Edition explains the structural complexities of proteins and enzymes and the mechanisms by which enzymes perform their catalytic functions. The book provides illustrative examples from the contemporary literature to guide the reader through concepts and data analysis procedures. Clear, well-written descriptions simplify the complex mathematical treatment of enzyme kinetic data, and numerous citations at the end of each chapter enable the reader to access the primary literature and more in-depth treatments of specific topics.

This Second Edition of Enzymes: A Practical Introduction to Structure, Mechanism, and Data Analysis features refined and expanded coverage of many concepts, while retaining the introductory nature of the book. Important new features include:

A new chapter on protein-ligand binding equilibria
Expanded coverage of chemical mechanisms in enzyme catalysis and experimental measurements of enzyme activity
Updated and refined discussions of enzyme inhibitors and multiple substrate reactions
Coverage of current practical applications to the study of enzymology
Supplemented with appendices providing contact information for suppliers of reagents and equipment for enzyme studies, as well as a survey of useful Internet sites and computer software for enzymatic data analysis, Enzymes, Second Edition is the ultimate practical guide for scientists and students in biochemical, pharmaceutical, biotechnical, medicinal, and agricultural/food-related research.


Pharmacotherapy of Diabetes: New Developments: Improving Life and Prognosis for Diabetic Patients

By Carl Erik Mogensen
Publisher: Springer
Number Of Pages: 318
Publication Date: 2007-09-05
ISBN-10 / ASIN: 0387697365
ISBN-13 / EAN: 9780387697369
Binding: Hardcover

Book Description:

In the United States, 20.8 million children and adults, 7% of the population, have diabetes. While an estimated 14.6 million have been diagnosed, 6.2 million have yet to be diagnosed. Worldwide diabetes afflicts 150 million people. The World Health Organization estimates that by 2025 that figure will double. Diabetes is responsible for more deaths than AIDS and breast cancer, combined. It is a leading cause of blindness, kidney failure, amputations, heart complications and stroke.

Treatment of Type 1 and Type diabetes has changed radically over the past few years. There are new opportunities for treating the key abnormality in diabetes, increased blood glucose, by effective agents such as new insulin preparations and oral agents.

Increasing so-called non-glycemic intervention is of prime importance. Blood pressure lowering therapies, anti-cholesterol strategies, and specific treatment related to complications is becoming increasingly important.

Pharmacotherapy of Diabetes is a unique, invaluable guide to all aspects of the pharmacological treatment of diabetes, covering basic concepts and an in-depth review of current and future therapies. This work provides an overview for the new changes in therapies that can be implemented in clinical practice and treatment of the diabetic patient.




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Glucokinase And Glycemic Disease: From Basics to Novel Therapeutics

Glucokinase And Glycemic Disease: From Basics to Novel Therapeutics (Frontiers in Diabetes)

Author: F. M. Matschinsky (Editor), M. A. Magnuson (Editor)
Product Details
406 pages, S. Karger Publishers (USA) (June 3, 2004) $234.75
Format: 2.5MB PDF
ISBN / ASIN: 3805577443
Summary:
The glucose-phosphorylating enzyme glucokinase (also known as hexokinase IV) plays a preeminent role as a glucose sensor and regulatory metabolic enzyme. The implications of this central position of glucokinase for the understanding and treatment of diabetes mellitus are far reaching. This book addresses the molecular and human genetic, as well as the physiological-chemical and pharmacological aspects of the role glucokinase plays in glucose homeostasis and diseases of glucose metabolism, and how the enzyme serves as the drug target for the treatment of diabetes mellitus. The collection of assays by a team of internationally renowned authors includes basic science chapters dealing with the enzymology, structure and the kinetics of hexokinases, essays describing the biochemical genetics of glucokinase-linked hypo- and hyperglycemia syndromes, and papers that discuss the diverse roles of the enzyme in a variety of tissues. 72981431


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Type 2 Diabetes, Pre-Diabetes, and the Metabolic Syndrome

Type 2 Diabetes, Pre-Diabetes, and the Metabolic Syndrome

By Ronald A. Codario
Publisher: Humana Press
Number Of Pages: 272
Publication Date: 2005-05-15
ISBN-10 / ASIN: 1588294714
ISBN-13 / EAN: 9781588294715
Binding: Hardcover
Book Description:

Well-known and highly respected diabetes authority Ronald A. Codario, MD, details for busy primary care practitioners the state of the art in diagnosing and managing diabetes, as well as in reducing patient risk factors. Using an evidence-based approach, Dr. Codario explains, in simple clinical terms that avoid the complexity of much larger textbooks, our latest understanding of the pathophysiology of diabetes, its treatment with insulin and oral agents, and the management of its risk factors. The author also extensively reviews such major topics as the metabolic syndrome, the role of exercise and nutrition, and the key issues associated with the use of herbs and nutraceuticals. Also included are continuing medical education (CME) questions that provide the opportunity to acquire up to a maximum of 10 AMA/PRA category 1 CME credits. For the past 15 years, the author has given CME lectures on diabetes throughout the country.


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Neural Development and Stem Cells

Neural Development and Stem Cells (Contemporary Neuroscience)



By Mahendra S. Rao

Publisher: Humana Press
Number Of Pages: 468
Publication Date: 2005-09-15
ISBN-10 / ASIN: 1588294811
ISBN-13 / EAN: 9781588294814
Binding: Hardcover

Book Description:

This extensively expanded and updated edition reflects the enormous increase in our knowledge of the development of the nervous system. Working from a new understanding that the regionalization of stem cells occurs early in development and that this bias appears to persist even after prolonged culture, Dr. Rao has added additional chapters on olfactory epithelial stem cells and retinal stem cells, both of which differ in their properties from ventricular zone and subventricular zone-derived neural stem cells. A new chapter on cell death summarizes the important changes in the death pathway that occurs as stem cells mature. Special attention is paid to the derivation of neural cells from embryonic stem cells. Authoritative and up-to-date, Neural Development and Stem Cells, Second Edition provides neuroscientists with a handy guide to stem cells in the nervous system, tracing with great clarity the development of stem cells from differentiation to neurons, astrocytes, and oligodendrocytes.



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Stress and Hypertension: Examining the Relation between Psychological Stress and High Blood Pressure


Stress and Hypertension: Examining the Relation between Psychological Stress and High Blood Pressure (Current Perspectives in Psychology)



By Kevin T. Larkin
Publisher: Yale University Press
Number Of Pages: 416
Publication Date: 2005-11-11
ISBN-10 / ASIN: 0300106440
ISBN-13 / EAN: 9780300106442
Binding: Hardcover
Book Description:

Does living a stress-filled life lead to elevated blood pressure? And if so, do strategies to better manage stress effectively lower blood pressure? In this authoritative and comprehensive book, Kevin T. Larkin examines more than a half-century of empirical evidence obtained to test the common assumption that stress is associated with the onset and maintenance of essential hypertension (high blood pressure).

While the research confirms that stress does play a role in the exacerbation of essential hypertension, numerous other factors must also be considered, among them obesity, exercise, and smoking, as well as demographic, constitutional, and psychological concerns. The author discusses the effectiveness of strategies developed to manage stress and thereby lower blood pressure and concludes with suggestions and directions for further study.



Angiogenesis and Direct Myocardial Revascularization

  • Angiogenesis and Direct Myocardial Revascularization (Contemporary Cardiology)
  • Publisher: Humana Press
  • Number Of Pages: 372
  • Publication Date: 2005-05-15
  • Sales Rank: 2305923
  • ISBN / ASIN: 1588291537
  • EAN: 9781588291530
  • Binding: Hardcover
  • Manufacturer: Humana Press
  • Studio: Humana Press
  • Average Rating: 0
  • Total Reviews: 0



Book Description:

An interdisciplinary panel of pioneers and opinion leaders review the basic, preclinical, clinical, and developmental pathways to new treatment strategies, such as therapeutic angiogenesis and myogenesis. The authors take advantage of new biological understanding, novel therapeutic targets, multiple available and well-studied therapeutic strategies, and the necessary imaging techniques to measure outcomes. Their in-depth discussions cover the identification of new therapeutic targets and pathways, the investigation of transcriptional factors, master switch molecules, cell-based approaches, chemokines, a better understanding of the effects of aging, endothelial dysfunction, and hypercholesterolemia in response to angiogenic stimuli. Highlights include examination of drug delivery problems, outcomes measure, stem therapy, high-risk interventions, development pathways, and future possibilities.



Drugs of Abuse: Body Fluid Testing

Drugs of Abuse: Body Fluid Testing (Forensic Science and Medicine)




  • Publisher: Humana Press
  • Number Of Pages: 320
  • Publication Date: 2005-06-16
  • Sales Rank: 1795791
  • ISBN / ASIN: 1588294358
  • EAN: 9781588294357
  • Binding: Hardcover
  • Manufacturer: Humana Press
  • Studio: Humana Press
  • Average Rating: 0
  • Total Reviews: 0


Book Description:

A comprehensive review of the science of drug testing in all its aspects, placing emphasis on technologies that use body fluids other than urine for determining the presence of drugs of abuse. The authors discuss the various body fluid specimens suitable for testing for illicit drugs-particularly saliva, sweat, and hair-describe the structural and manufacturing aspects of on-site testing devices based on lateral flow immunoassay, and detail the pitfalls of using these specimens. They also discuss in detail the problem of sample adulteration and its detection. Since oral fluid has the best potential of succeeding urine as the next matrix of choice for drug detection, four popular saliva testing devices are examined: Intercept®, the Drager Drug Test®, Oratect®, and Drugwipe. Political, social, and legal issues are also considered in articles on privacy, the use of drug testing in courts, and the problem of sample adulteration.

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Tuesday, November 6, 2007

Cancer: Cell Structures, Carcinogens and Genomic Instability

Product Details
»Book Publisher: Birkhauser (07 December, 2005)
»ISBN: 3764371560
»Book author: Leon P. Bignold
»Amazon Rating:

Book Description:
Tumors can be induced by a variety of physical and chemical carcinogens. The resulting tumor cells are usually abnormal in their morphology and behavior and transmit their abnormalities to their daughter tumor cells. Most theories of the pathogenesis of tumors suggest that carcinogens in some way cause alterations either of the genomes or of inheritable patterns of gene expression in normal cells, which then cause morphological and behavioral changes. This volume presents a collection of articles aimed at the question by what genetic or epigenetic mechanisms carcinogens can cause morphological abnormalities of tumor cells.Section 1 provides reviews of the known abnormalities of cell structures, including chromatin, nuclear matrix, cytoplasmic constituents and plasma membranes of tumor cells. Section 2 provides reviews of cellular targets of known carcinogens. Section 3 presents varying viewpoints of how morphological abnormalities of tumor cells and the actions of carcinogens might be related. The volume will be of interest to all those who are involved in cancer research or in the prevention, diagnosis or management of tumors in humans or animals

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Multiple Sclerosis: Immunology, Pathology and Pathophysiology

Product Details
»Book Publisher: Demos Medical Publishing (January, 2003)
»ISBN: 1888799625
»Book author: Robert M. Herndon
»Amazon Rating:

Book Description:
Univ. of Mississippi, Jackson. Provides an overview of the basic sciences as they relate to MS. Companion text to, Multiple Sclerosis: Diagnosis, Medical Management, and Rehabilitation by Jack S. Burks, c2000. Includes halftone charts, and illustrations. Topics include morphologic substrates of demyelination, experimental aspects, and more. DNLM: Multiple Sclerosis–immunology.

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Essentials of Pathophysiology: Concepts of Altered Health States

Product Details
»Book Publisher: Lippincott Williams & Wilkins (01 July, 2003)
»ISBN: 0781746450
»Book author: Carol Mattson Porth
»Amazon Rating: 4.5

Book Description:

Designed to provide students with essential concepts of disease processes and altered health states, Essentials of Pathophysiology is ideal for both discrete and integrated pathophysiology courses. This abundantly illustrated text is extremely readable and filled with learning tools to highlight important ideas for the reader. Key concept boxes draw attention to important facts, color-coded summaries clarify complex processes discussed throughout the chapters, and icons appear throughout the text highlighting appropriate considerations for children, the elderly, and pregnant women. The free CD-ROM contains 3-D animations, and also contains more than 500 multiple-choice questions to test the reader’s knowledge of difficult concepts. In keeping with the author’s philosophy, Essentials of Pathophysiology relates normal body functioning to the physiologic changes that participate in disease production and occur as a result of the disease. Content is arranged so that concepts build upon one another, thus promoting conceptual understanding as opposed to memorization. Additional resources are available at the Connection Website, connection.LWW.com/go/porthessentials.

Surgical Pathology Dissection: An Illustrated Guide

Product Details
»Book Publisher: Springer (30 April, 2003)
»ISBN: 0387955593
»Book author: William H. Westra, Ralph H. Hruban, Timothy H. Phelps, Christina Isacson, F.B. Askin
»Amazon Rating: 4.0

Book Description:

Surgical Pathology Dissection, Second Edition fills the need for a comprehensive, fully illustrated guide to the preparation, dissection, and handling of surgical pathology specimens. The authors share their wealth of talent and experiences by providing general principles that can be employed to resolve even the most complex problems in dissection and tissue sampling. The descriptive text is augmented by 62 exclusive, detailed illustrations printed as full-page plates depicting proper specimen handling techniques that add a unique vitality and multidimensional effect. Each chapter features a section on Important Issues to Address in Your Surgical Pathology Report and references selected for their pertinent coverage of specimen handling for each organ system.

Updated and revised, this second edition includes four new chapters and expanded discussions on: Preparation of Tissues for Molecular Analysis; Craniofacial Bones; Heart; Transplantation Specimens; The Sentinel Lymph Node. Revisions have been made to conform to suggested guidelines proposed by the College of American Pathologists.

From reviews of the first edition:

“Hruban, Westra and Isacson, working with a superb medical illustrator did an admirable job in taking the Johns Hopkins’ gross room manual and translating it into a practical, concise, and easily accessible guide to contemporary practice in the surgical pathology laboratory.”

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  • Cancer Metastasis — Related Genes

    Product Details
    »Book Publisher: Springer (01 May, 2002)
    »ISBN: 1402005229
    »Book author: D.R. Welch
    »Amazon Rating:

    Book Description:
    This volume is the first attempt to summarize current knowledge about the underlying molecular and biochemical mechanisms controlling the metastatic phenotype. While all previous authors attempted to put their findings into a context for translation to the clinical situation, the state of the art does not fully allow this because the field of metastasis is relatively new. Nonetheless, the contents of this volume will be of use to members of the cancer research community and clinicians interested in developing and implementing novel forms of treatment for cancer.

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    Cancer: Principles & Practice Of Oncology (2 Vol. Set)(7th Edition)

    Product Details
    »Book Publisher: Lippincott Williams & Wilkins (01 December, 2004)
    »ISBN: 0781748658
    »Book author: Vincent T Devita, Samuel Hellman, Steven A Rosenberg
    »Amazon Rating:

    Book Description:

    Acclaimed by the worldwide medical community as “the ultimate authority on cancer” (JAMA), Cancer: Principles and Practice of Oncology is now in its Seventh Edition. This completely revised, updated classic reflects the latest breakthroughs in molecular biology, cancer prevention, and multimodality treatment of every cancer type.
    New chapters examine molecular biologic techniques including proteomics, genomics, targeted therapies, RNA interference, cDNA arrays, and tissue arrays. New sections discuss bioinformatics and societal issues in oncology, including regulatory issues, telemedicine, and international differences in oncology. Coverage also includes new information on functional and metabolic imaging, vaccines, and antiangiogenesis agents.
    A bound-in CD-ROM includes the full text, color slides, and PubMed links.

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  • Molecular Biology in Cellular Pathology

    Product Details
    »Book Publisher: John Wiley & Sons (09 June, 2003)
    »ISBN: 0470844752
    »Book author: John Crocker, Paul G. Murray
    »Amazon Rating:

    Book Description:
    The latest edition of this highly successful text, covers the major advances in the methods used in cellular and molecular pathology. In recent years, knowledge of the molecular organization of the cell has led to the development of powerful new techniques that bring greater accuracy and objectives to the diagnosis, prognosis and management of many diseases and to the study of pathological states. This book describes the latest molecular techniques available for the analysis of diseases. In particular it includes new techniques using fluorescent dyes, DNA microarrays, protein chemistry, and mass spectrometry. It also incorporates information from the Human Genome Project, and the new disciplines of genomics and proteomics, where relevant to pathology. Color plates are a new feature of this edition, illustrating the advances in fluorescence labeling of cells.

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    Cell Seperation

    Product Details
    »Book Publisher: Oxford University Press (26 November, 1998)
    »ISBN: 019963579X
    »Book author: Derek Fisher, Gillian E. Francis, D. Rickwood
    »Amazon Rating: 4.0

    Book Description:
    This book is unique in that it brings together the best methods currently available for separating cells. For each approach, the authors provide clear explanations of the theoretical basis of the procedures as well as practical details of the technique.

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    Color Atlas Of Forensic Pathology

    Product Details
    »Book Publisher: CRC (21 December, 1999)
    »ISBN: 0849302781
    »Book author: Jay Dix
    »Amazon Rating: 3.0

    Book Description:

    This extensive atlas addresses much of the basic information which forensic pathologists and other investigators deal with on a day to day basis. Packed with 800 full-color, captioned photographs, it examines everything from time of death and decomposition, to identification, blunt trauma, sudden natural death, firearm injuries, asphyxia, cutting and stabbing injuries, and more. The atlas shows different causes of death and injury with case examples for investigators who can use ‘visuals’ to understand the work they perform.

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  • Brain Tumor Pathology: Current Diagnostic Hotspots and Pitfalls

    Product Details
    »Book Publisher: Springer (11 April, 2006)
    »ISBN: 1402039972
    »Book author: Davide Schiffer
    »Amazon Rating:

    Book Description:

    This book is not a treatise on brain tumor pathology and nosography. It has been conceived as a help to pathologists, neuropathologists and neuro-oncologists in confronting everyday problems arising in the diagnostics of brain tumors.

    The initial chapters cover the distinction between infiltrating tumors and normal nervous tissue, between diffuse astrocytoma and oligodendroglioma and the identification of the malignant variant of some tumor types. Moreover, in the pathology of brain tumors, some biological processes are active which show a development over the course of time, such that in surgical samples they cannot be recognized as a whole, but only from the occurrence of limited and partial aspects. Invasion modalities, angiogenesis and apoptosis fall in this category and are discussed not in an exhaustive manner, but as stages or phases of the processes identified in the tissue.

    The figures do not seek to illustrate the characteristic aspects of the tumors, but only the points under discussion.This book is the result of many years of personal experience in the diagnosis of brain tumors as well as of discussions with neurosurgeons and neuro-oncologists and it aspires to contribute to solving emerging everyday problems.

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  • Forensic Neuropathology and Neurology

    Product Details
    »Book Publisher: Springer (27 September, 2005)
    »ISBN: 3540235000
    »Book author: Manfred Oehmichen, Roland N. Auer, Hans G. K├Ânig, Kurt A. Jellinger
    »Amazon Rating: 5.0

    Book Description:

    Incorporating the most recent literature and state-of-the-art methods, this practical work and atlas covers the entire domain of neuropathology for forensic pathologists as well as for specialists in associated fields. Its concise, direct style provides the reader with succinct and easy-to-find answers to forensic, pathological, pathophysiological, biomechanical, and molecular biology problems. Additionally, the authors cover several basic and practical problems that may stimulate further research.

    Each chapter includes an overview of the literature as well as specified references, and features a wealth of figures, graphs, and tables.

    The present volume deals with specific aspects of neuropathology, and is particularly appropriate for all those interested and involved in the field of forensic pathology, forensic sciences, clinical pathology, neurology, neurosurgery, law, and criminology. Special emphasis is placed on expertise concerning the field’s relevance for everyday practice and also on up-to-date data in basic research.

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  • Manual of Diagnostic Antibodies for Immunohistology

    Product Details
    »Book Publisher: Greenwich Medical Media (01 December, 2002)
    »ISBN: 1841101001
    »Book author: Anthony S-Y. Leong, Kumarasen Cooper, F. Joel W-M. Leong
    »Amazon Rating: 5.0

    Book Description:
    The rapid acceptance of immunohistochemistry as an important and even indispensable adjunct to morphological examination and diagnosis requires the modern anatomical pathology laboratory to be conversant with, and proficient in, immunostaining procedures, as well as methods of tissue processing and antigen retrieval and the underlying characteristics of the increasing number of antibodies and antisera available. This fully revised, expanded and updated edition provides a comprehensive list of antisera and monoclonal antibodies that have useful diagnostic applications in tissue sections and cell preparations. Various clones, which are commercially available to detect the same antigen, are listed and the sensitivities and specificities of the antibodies are discussed. Importantly, the authors, all pathologists with a wealth of experience in immunostaining procedures, provide fully referenced details and expert advice on each reagent, which the reader will find invaluable. Finally, the appendices provide easily accessible and clear summaries of selected antibody panels for specific diagnostic situations, details of heat-induced antigen/epitope retrieval (including the use of microwaves) and a useful reference to the websites of the main antibody suppliers

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  • Ross and Wilson: Anatomy and Physiology in Health and Illness

    Product Details
    »Book Publisher: Churchill Livingstone (15 July, 2001)
    »ISBN: 0443064687
    »Book author: Anne Waugh, Allison Grant
    »Amazon Rating: 5.0

    Book Description:
    Here’s an easy-to-read and easy-to-understand basic textbook of anatomy and physiology. Highly illustrated full-color photos are used throughout. In addition to covering the “normal” anatomy and physiology, each chapter ends with a brief section on diseases which explains what happens when the “normal” goes wrong. The text provides the essential foundations of understanding for all students studying health-related courses.

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    Ross and Wilson: Anatomy and Physiology in Health and Illness

    Product Details
    »Book Publisher: Churchill Livingstone (15 July, 2001)
    »ISBN: 0443064687
    »Book author: Anne Waugh, Allison Grant
    »Amazon Rating: 5.0

    Book Description:
    Here’s an easy-to-read and easy-to-understand basic textbook of anatomy and physiology. Highly illustrated full-color photos are used throughout. In addition to covering the “normal” anatomy and physiology, each chapter ends with a brief section on diseases which explains what happens when the “normal” goes wrong. The text provides the essential foundations of understanding for all students studying health-related courses.

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    Color Atlas of Histopathology of the Cervix Uteri

    Product Details
    »Book Publisher: Springer (26 October, 2005)
    »ISBN: 354025188X
    »Book author: Gisela Dallenbach-Hellweg, Magnus von Knebel Doeberitz, Marcus J. Trunk
    »Amazon Rating:

    Book Description:

    The second edition of this atlas provides a detailed histopathological diagnosis of cervical disease emphasizing carcinogenesis, and correlating morphologic changes with clinical aspects. Instructions of how to obtain and handle tissue samples are followed by a description of the normal histology, of the action of steroid hormones on the cervix, and of the various forms of regeneration and inflammation. The section on etiology and pathogenesis of HPV-induced neoplasia has been enlarged to explain new insights into cellular and nuclear deregulation at the molecular level. A chapter on immunohistochemistry has been added which includes refined detection methods, e.g., with p16 for the early differential diagnosis of premalignant lesions. The latest advances in molecular biological research, with predictive subdivision of neoplasias, facilitate the choice of the proper therapy. All chapters – supported by over 20 new microphotographs – have been revised to include advances in the interpretation and management of cervical disease. The tumor nomenclature is adapted to the new WHO classification; the ICD-O code has been added. The reference list is updated with relevant publications.

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    Colorectal Cancer: Methods and Protocols

    Product Details
    »Book Publisher: Humana Press (15 January, 2001)
    »ISBN: 0896037673
    »Book author: Steven M. Powell
    »Amazon Rating:

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    Manual of Diagnostic Antibodies for Immunohistology

    Product Details
    »Book Publisher: Greenwich Medical Media (01 December, 2002)
    »ISBN: 1841101001
    »Book author: Anthony S-Y. Leong, Kumarasen Cooper, F. Joel W-M. Leong
    »Amazon Rating: 5.0

    Book Description:
    The rapid acceptance of immunohistochemistry as an important and even indispensable adjunct to morphological examination and diagnosis requires the modern anatomical pathology laboratory to be conversant with, and proficient in, immunostaining procedures, as well as methods of tissue processing and antigen retrieval and the underlying characteristics of the increasing number of antibodies and antisera available. This fully revised, expanded and updated edition provides a comprehensive list of antisera and monoclonal antibodies that have useful diagnostic applications in tissue sections and cell preparations. Various clones, which are commercially available to detect the same antigen, are listed and the sensitivities and specificities of the antibodies are discussed. Importantly, the authors, all pathologists with a wealth of experience in immunostaining procedures, provide fully referenced details and expert advice on each reagent, which the reader will find invaluable. Finally, the appendices provide easily accessible and clear summaries of selected antibody panels for specific diagnostic situations, details of heat-induced antigen/epitope retrieval (including the use of microwaves) and a useful reference to the websites of the main antibody suppliers.

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    Principles of Molecular Pathology

    Product Details
    »Book Publisher: Humana Press (December, 2003)
    »ISBN: 1588290859
    »Book author: Anthony A. Killeen
    »Amazon Rating:

    Book Description:
    This is a very nice, concise review of the field of molecular pathology, a field that is still considered “new” because it requires training in several fields, including pathology, molecular methods, genetics, infectious disease, and tumor biology. The book provides readers with all of the relevant background in the first chapters so that specialists and nonspecialists alike can understand the later chapters. It can be read from cover to cover or used as a reference text on an “as-needed” basis. Considering the diversity of molecular pathology, the book is relatively short, 333 pages, but it provides a comprehensive review of the field. I particularly liked how each chapter highlighted all of the salient points of the subject material and then went on to illustrate many of the exceptions.

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    Histopathology Specimens: Clinical, Pathological and Laboratory Aspects

    Product Details
    »Book Publisher: Springer (31 January, 2004)
    »ISBN: 1852335971
    »Book author: Derek C. Allen, R. Iain Cameron
    »Amazon Rating:

    Book Description:

    Covering anatomical, clinical, pathological and laboratory aspects of surgical histopathology specimens, this book relates specimen dissection and its clinical context to relevant histopathology reports, and therefore a more comprehensive patient prognosis and management is possible.

    Histopathology Specimens - Clinical, Pathological and Laboratory Aspects explains pathological and clinical terminology, including a glossary of clinical request form abbreviations. It offers a standardised step-wise approach to specimen handling illustrated by simple line diagrams and highlights essentials of the histopathology report, relating them to appropriate specimen dissection.

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    Cancer Cytogenetics: Methods and Protocols

    Product Details
    »Book Publisher: Humana Press (April, 2003)
    »ISBN: 1588290808
    »Book author: John Swansbury
    »Amazon Rating:

    Book Description:
    The Royal Marsden NHS Trust, Surrey, UK. Text describes in detail the key cytogenetic and FISH techniques used in the genetic analysis of human malignancies and how to interpret the results. Each protocol contains novel ideas and time-saving techniques. Also provides guidance on the significance and interpretation of findings.

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    Pathology And Genetics of Tumours of the Soft Tissues And Bones

    Product Details
    »Book Publisher: Not Avail (January, 2003)
    »ISBN: 9283224132
    »Book author: Who
    »Amazon Rating: 5.0

    Book Description:
    This book is an authoritative, concise reference, prepared by 147 authors from 28 countries. It contains more than 800 colour photographs, numerous MRIs, ultrasound images, CT scans, charts and approximately 2000 references. Diagnostic criteria, pathological features and associated genetic alterations are described in a strictly disease-oriented manner. Sections on all recognized neoplasms and their variants include new ICD-O codes, incidence, age and sex distribution, location, clinical signs and symptoms, pathology, genetics and predictive factors.

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  • Handbook of Pathophysiology


    Product Details
    »Book Publisher: Lippincott Williams & Wilkins (15 January, 2001)
    »ISBN: 1582550468
    »Book author: Springhouse
    »Amazon Rating: 5.0


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    BRS Pathology


    Product Details
    »Book Publisher: Lippincott Williams & Wilkins (November, 2002)
    »ISBN: 0781743176
    »Book author: Arthur S. Schneider, Philip A. Szanto, Todd A. Swanson, Sandra I. Kim
    »Amazon Rating: 4.5

    Book Description:
    This top-selling title is now in its Second Edition. An excellent preparatory review for course exams or the USMLE Step 1, the chapters parallel most standard pathology texts plus provide a review test at the end of each chapter. Topics covered include general and basic pathology, major concepts of disease processes, and systemic pathology surveying principal disorders of each organ system. A comprehensive examination at the end of the book contains 500 questions in USMLE format. New features include key associations throughout the text that emphasize “high-yield” information for the USMLE review and a new chapter entitled Interpretation of Diagnosis Tests (laboratory statistics)

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    Diagnostic Atlas of Renal Pathology: A Companion to Brenner and Rector’s The Kidney 7E

    Product Details
    »Book Publisher: Saunders (17 May, 2005)
    »ISBN: 1416028714
    »Book author: Agnes B. Fogo, Michael Kashgarian
    »Amazon Rating: 5.0

    Book Description:
    This new atlas covers all major inflammatory, infectious, pre-neoplastic, and neoplastic diseases of the kidney. Over 600 illustrations help readers to recognize the pathologic features and clinical manifestations of both common and rare renal disorders and to formulate confident and accurate diagnoses. This resource, Diagnostic Atlas of Renal Pathology, is designed as a companion book to, The Kidney 7th Edition by Brenner and Rector. The newest information regarding categorizing and classification of diseases is presented and how this relates to the various morphological lesions illustrated and their clinical significance.

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    The Sentinel Lymph Node Concept

    Product Details
    »Book Publisher: Springer (15 October, 2004)
    »ISBN: 3540410414
    »Book author: A.J. Schauer, W. Becker, M. Reiser, K. Possinger, Alfred Schauer, Wolfgang Becker, Maximilian F. Reiser, Kurt Possinger
    »Amazon Rating:

    Book Description:

    The Sentinel Lymph Node Concept is evaluated from the points of view of pathology, radiodiagnosis and nuclear medicine diagnostics, surgical treatment and clinical oncology. The concept and its practical applications are analyzed for breast cancer, malignant melanoma, tumors of the face, oropharynx, lung, gastrointestinal and urogenital tracts. The first part of the book describes the function and use of the nuclear medicine equipment, the tracers used, colloid solutions and modern developments in histological and immunohistochemical lymph node investigations, as well as possible pitfalls. The consequences of false-negative results are clearly delineated. In the second part, specific tumor-related problems are described.

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    Pharmacotherapy

    Product Details
    »Book Publisher: McGraw-Hill Medical (12 May, 2005)
    »ISBN: 0071416137
    »Book author: Joseph T. DiPiro, Robert L. Talbert, Gary C. Yee, Gary R. Matzke, Barbara G. Wells, L. Michael Posey
    »Amazon Rating: 4.5

    Book Description:
    The gold standard text for the therapeutics course mandatory in pharmacy schools. Now in its sixth edition, this classic text continues its long-standing tradition of offering unparalleled guidance in the development of pharmaceutical care plans. The book provides a unique process of thinking about pharmacotherapy the process which uses evidence-based approaches to the drug treatment of diseases.

    Features:
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    *NEW Key Concepts begin each chapter
    *Excellent use of algorithms, tables, and charts – provides clear recommendations
    *“Clinical Controversies” in the treatment sections of disease-oriented chapters

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  • Oxford Textbook of Oncology (2 volume set)

    Product Details
    »Book Publisher: Oxford University Press, USA (01 December, 2001)
    »ISBN: 0192629263
    »Book author: Robert Souhami, Ian Tannock, Peter Hohenberger, Jean-Claude Horiot
    »Amazon Rating:

    Book Description:
    The Oxford Textbook of Oncology provides the definitive, international reference on clinical cancer medicine. It combines the experience of the world’s leading cancer experts, particularly from leading European centres of excellence, with an approach that emphasizes the importance of the best clinical evidence: the guidelines to management are based on the sum of all the available evidence. For rare tumours, where clinical experience is the main guide to treatment, the editors have ensured that options and alternatives are discussed. There are major sections on all cancer sites, and in each section investigation, epidemiology, pathology, causes and treatment are covered in a consistent manner to aid reference. There is a new international team of editors for the second edition, representing oncology, radiotherapy and surgery. Two-thirds of the text has been entirely rewritten. The chapters have been carefully reviewed to ensure that they are clear and concise. Quality-of-life and psychosocial issues, palliation, and communication are given fuller treatment. Early chapters describe the processes underlying cancer; the information on the molecular and cellular biology of cancer and their practical impact on diagnosis and investigative procedures have been extensively revised and updated. The sections on the scientific basis of cancer treatment include the principles of the use of surgery, radiation, chemotherapy and biological therapies. There are substantial new sections on adolescent cancer, cancer as a genetic disease, and melanoma and skin cancer and the extensive section on breast cancer is now in proportion to the importance and frequency of this disease. The many clear illustrations are prepared to a consistently high quality. The Oxford Textbook will be the reference work of choice for oncologists, both in practice and in training, all over the world. It will also be an important reference work for generalists who need to understand modern cancer management as part of their practice.

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    Pathology Illustrated

    Product Details
    »Book Publisher: Churchill Livingstone (January, 2000)
    »ISBN: 044305956X
    »Book author: Peter S. Macfarlane, Robin Reid, Robin Callander
    »Amazon Rating: 5.0

    Book Description:
    Generations of medical students have been helped to pass their exams by the “Illustrated” books. The visual presentation of the subject matter, divided into one-page units, makes for easy learning and re-call. Pathology is central to the study of medicine and forms the bridge between the basic sciences and clinical medicine, making this book a key purchase.

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    Antiviral Drug Discovery for Emerging Diseases and Bioterrorism Threats

    Product Details
    »Book Publisher: Wiley-Interscience (03 August, 2005)
    »ISBN: 0471668273
    »Book author: Paul F. Torrence
    »Amazon Rating:

    Book Description:
    Antiviral Drug Discovery gives readers a cutting-edge view of how chemical concepts are being mobilized to develop novel approaches that will effectively confront emerging diseases and biowarfare. Among the many topics discussed are smallpox, the Ebola virus, influenza, SARS, arenaviruses and flaviviruses. Each chapter discusses hypothetical strategies for the discovery of relevant antiviral agents, recent findings related to biochemistry or drug discovery, and advances in the further development of established leads in the area. Timely and informative, this book clearly delineates the efforts being made to develop new and effective broad-spectrum antiviral agents.

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    Blackwell Underground Clinical Vignettes Pathophysiology II: GI, Neurology, Rheumatology, Endocrinology

    Product Details
    »Book Publisher: Lippincott Williams & Wilkins (01 May, 2005)
    »ISBN: 1405104155
    »Book author: Vikas Bhushan, Vishal Pall, Tao Le
    »Amazon Rating:

    Book Description:

    Blackwell Underground Clinical Vignettes: Pathophysiology II, Fourth Edition is your primary source for clinically relevant, case-based material essential for USMLE Step 1 review. Each Clinical Vignette simulates USMLE format, and includes classic buzzwords in history taking, physical examination, lab, imaging, and pathology. This volume, Pathophysiology II, covers the gastrointestinal system, neurology, rheumatology, and endocrinology; Pathophysiology I covers pulmonary, OB/GYN, ENT, and hematology/oncology; and Pathophysiology III covers the cardiovascular system, dermatology, the genitourinary tract, and general surgery. This revised edition contains: / Carefully selected cases templated to fit the way you are tested and taught to think / Valuable links to Step 1 and 2 Atlases for emphasis on photographic case studies / Over 50 new cases compatible with the updated content of USMLE Step 1 Blackwell Underground Clinical Vignettes: Pathophysiology

    Blackwell Underground Clinical Vignettes Pathophysiology III: CVS, Dermatology, GU, General Surgery

    Product Details
    »Book Publisher: Lippincott Williams & Wilkins (01 May, 2005)
    »ISBN: 1405104163
    »Book author: Vikas Bhushan, Vishal Pall, Tao Le
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    Pathophysiology of Disease: An Introduction to Clinical Medicine

    Product Details
    »Book Publisher: McGraw-Hill Medical (04 November, 2005)
    »ISBN: 007144159X
    »Book author: Stephen J. McPhee, Vishwanath R. Lingappa, William F. Ganong
    »Amazon Rating: 3.5

    Book Description:
    Now in its Fifth Edition, this trusted guide provides medical students with the link between basic science and clinical medicine. This concise text covers all the essentials in pathophysiology and 89 case studies allow students to apply their knowledge to actual clinical situations.

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    High-Yield Pathology

    Product Details
    »Book Publisher: Lippincott Williams & Wilkins (September, 2000)
    »ISBN: 0781723671
    »Book author: Ivan Damjanov
    »Amazon Rating: 1.0

    Book Description:
    Univ. of Kansas, Kansas City. Text designed to provide an uncomplicated review of pathology, and equip the reader for the pathology questions on the USMLE Step 1. Written in outline format for quick review. Softcover. DNLM: Pathology–Examination Questions.

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  • Robbins Pathologic Basis of Disease, 6th edition

    Product Details
    »Book Publisher: W.B. Saunders Company (15 January, 1999)
    »ISBN: 072167335X
    »Book author: Ramzi S. Cotran, Vinay Kumar, Tucker Collins, Stanley L. Robbins
    »Amazon Rating: 4.5

    Book Description:
    First Prize (Basic and Clinical Sciences), 2005 BMA Awards
    Through six editions, Robbins Pathologic Basis of Disease has been the leading textbook in its field. No other resource has been able to match its outstanding coverage of pathophysiology and disease. Now renamed Robbins and Cotran Pathologic Basis of Disease, the new, 7th Edition of this classic text delivers a host of improvements that make it an even clearer choice for students and practitioners!

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  • Blackwell Underground Clinical Vignettes PathophysiologyI: Pulmonary, Ob/Gyn, ENT, Hem/Onc

    Product Details
    »Book Publisher: Lippincott Williams & Wilkins (01 May, 2005)
    »ISBN: 1405104147
    »Book author: Vikas Bhushan, Vishal Pall, Tao Le
    »Amazon Rating:

    Book Description:

    Blackwell Underground Clinical Vignettes: Pathophysiology I, Fourth Edition is your primary source for clinically relevant, case-based material essential for USMLE Step 1 review. Each Clinical Vignette simulates USMLE format, and includes classic buzzwords in history taking, physical examination, lab, imaging, and pathology. This volume, Pathophysiology I, covers pulmonary, OB/GYN, ENT, and hematology/oncology; Pathophysiology II covers the gastrointestinal system, neurology, rheumatology, and endocrinology; and Pathophysiology III covers the cardiovascular system, dermatology, the genitourinary tract, and general surgery. This revised edition contains: / Carefully selected cases templated to fit the way you are tested and taught to think / Valuable links to Step 1 and 2 Atlases for emphasis on photographic case studies / Over 50 new cases compatible with the updated content of USMLE Step 1 Blackwell Underground Clinical Vignettes: Pathophysiology I, Fourth Edition is perfect for medical students. Physician assistants, nurse practitioners, and related health professionals will also find Underground Clinical Vignettes valuable.

    Color Atlas of Pathology: Pathologic Principles-Associated Diseases-Sequela

    Product Details
    »Book Publisher: Thieme Medical Publishers (October, 2004)
    »ISBN: 1588901173
    »Book author: Ursus-Nikolaus, M.D. Riede, Martin Werner
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    Robbins & Cotran Pathologic Basis of Disease

    Product Details
    »Book Publisher: Saunders (30 July, 2004)
    »ISBN: 0721601871
    »Book author: Vinay Kumar, Nelso Fausto, Abul Abbas
    »Amazon Rating: 4.5

    Book Description:
    First Prize (Basic and Clinical Sciences), 2005 BMA Awards
    Through six editions, Robbins Pathologic Basis of Disease has been the leading textbook in its field. No other resource has been able to match its outstanding coverage of pathophysiology and disease. Now renamed Robbins and Cotran Pathologic Basis of Disease, the new, 7th Edition of this classic text delivers a host of improvements that make it an even clearer choice for students and practitioners!

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